Bringing books for your children on your flight can be a great way to pass the time. If your kids are old enough, they can obviously bring and read their own book. For younger kids, you can bring some of their favorite picture books along, and maybe some good new ones on airplanes, travel and flying.
These days, portable DVD players, and various audio players are also an option on board, and so are different types of apps. For example, the company Tales2Go offers an app for various Apple devices (like iphones, ipads, and ipods) making it possible for your children to listen to any of the stories available in their library. I haven't tried this app myself, but it definitely sounds like an easy and convenient way to bring some stories with you when you're traveling.
Downloading some audio books for your children to listen to on your trip can also be a good way to keep them entertained at airports and on board.
Whether you choose books or audio, both fiction and non-fiction stories travel and airplanes can be a good choice, and can help make the trip more fun and also less scary for kids (and adults!) who are worried about flying or being away from home.
For kids who are a little older, or just really into the technical aspects of airplanes and air travel, there are many books out there, for example "All Aboard Airplanes
Some good kids' books for varying ages that feature a lot of travel are the Toot and Puddle series, the Tintin comic books, and why not Jules Verne's "Around the World in 80 Days"